20% Mannitol
Test dose:
Adult/Pedia: 200 mg/kg or 1 mL/kg within 10 min.
If with good urine output (>1mL/kg/hr), continue at initial
dose of 0.5-1.0 g/kg or 2.5-5.0 mL/kg
Maintenance dose (if kidney function is good):
Adult: 75-100 mL q 6 hours
Pedia: 0.25-0.5 g/kg/dose or 1.0-2.5 mL/kg/dose q 6
hours
If diuresis does not occur in 2 hours, discontinue Mannitol.
Duration of mannitol treatment will depend on the half-life of the ingested poison, but usually should not exceed 48 hours.