Hepatitis B special initiative

Measure it

Measuring chronic infection rates among vaccinated cohorts is critical for monitoring the impact of vaccination programmes. The Western Pacific Region has accumulated valuable resources and experience in conducting hepatitis B serosurveys for monitoring the status of hepatitis B control.

Country Resources and Experiences

Links to Resources

Key References

Bialek SR, Helgenberger L, Fischer GE, Bower WA, Konelios M Chaine JP, Armstrong G, Williams IT, Bell BP. Impact of Routine Hepatitis B Immunization on the Prevalence of Chronic Hepatitis B Virus Infection in the Marshall Islands and the Federated States of Micronesia. Pediatr Infect Dis J. 2010;29(1):18-22.

Liang X, Bi S, YangW, Wang L, Cui G, Cui F, Zhang Y, Liu J, Gong X, Chen Y, Wang F, Zheng H, Wang F, Guo J, Jia Z, Ma J, Wang H, Luo H, Li L, Jin S, Hadler SC, Wang Y. Epidemiological serosurvey of Hepatitis B in China—Declining HBV prevalence due to Hepatitis B vaccination. Vaccine. 2009;27:6550–6557.

Soeung SC, Rani M, Huong V, Sarath S, Kimly C, Kohei T. Results from Nationwide Hepatitis B Serosurvey in Cambodia using Simple and Rapid Laboratory Test: Implications for National Immunization Program. Am J Trop Med Hyg. 2009; 81(2):252–257.

Danielsson N, Fakakovikaetau T. Szegedi E. Improved immunization practices reduce childhood hepatitis B infection in Tonga. Vaccine. 2000;27:4462–4467.

Wilson N, Ruff TA, Rana BJ, Leydon J, Locarnini S. The effectiveness of the infant hepatitis B immunisation program in Fiji, Kiribati, Tonga and Vanuatu. Vaccine. 2000; 18:3059-3066.