Emerging disease surveillance and response

Avian Influenza

Avian Influenza Weekly Update Number 386 (14 June 2013)

Latest information on human avian influenza A(H5N1) cases

Since 2003 to 14 June 2013, the number of cases reported from 15 countries worldwide is 630 and 375 were fatal (CFR 59.5%). Among the countries with more than 10 reported cases, Cambodia had the highest CFR of 84.3% (27 out of 32).

Age distribution of the reported cases ranged from 3 months to 81 years old (median 18 years, n=607). The age group with the largest number of cases was 20-29 years of age (22.6%, 137/607), relative to other age groups (0-4; 5-9; 10-19; 30-39; 40-49; 50-59; 60-69; 70+ years). The highest CFR (74.0%) was among persons 10-19 years of age and lowest was among persons 70+ years old (25.0%). 53.9% of the cases were female (326/605). However, age and sex distributions vary by country.

Table 1: Cumulative Number of Confirmed Human Cases (C) and Deaths (D) of Avian Influenza A (H5N1) Reported to WHO

Total number of cases includes number of deaths.
WHO reports only laboratory-confirmed case. All dates refer to onset of illness.

Latest human avian influenza A (H5N1) cases in countries affected in 2012 (as of 14 June 2013)

Bangladesh. The first case in 2013, 1 year 11 month old male, from Chittagong. He had onset 11th February, hospitalized on 12th February and died (date to be confirmed).

Cambodia. The eleventh case, 5 year old female from Tep Phirom village, Veal Pon Commune, Thpong District, Kampong Speu province. Onset of illness was on 28 January 2013. The patient was enrolled in a fever surveillance study of the US Naval Medical Research Unit. She was confirmed positive to A/H5N1 influenza on 2 May 2013. The patient is alive. While poultry exposure was not definitively confirmed, it is strongly suspected based on retrospective investigations.

China. Two new human cases have been reported. The first case, a 21 year old female from Guiyang district, Guizhuo province confirmed positive to A/H5N1 influenza by Chinese Center for Disease Control on 10th February 2013. The patient was admitted to Guizhou Provincial People’s Hospita and died on 13 February. She had onset of symptoms on 02 February and she had no clear history of contacting poultry before symptom onset. The second case, a 31 year old male from Guiyang district, Guizhuo province was confirmed positive for A/H5N1 influenza by Guizhou Province CDC on 10th February 2013. The patient was admitted to the Guiyang City Second People's Hospital and later sent to intensive care unit and died on 22th February 2013. He had onset of symptoms on 03 February and had no clear history of contacting poultry before symptom onset. It was reported that there was no epidemiological linkage between the two cases.

Egypt. Two new cases reported in Egypt. The second case in 2013, 40 years old female, from Menofia. She developed symptoms on 3rd March, admitted to hospital on 8th March. She had history of sick poultry exposure. The third case in 2013, 26-year old male, from Elmanzala District, Dakalia Governorate. The man developed symptoms on 30 March 2013 and was admitted to a hospital on 5 April where he was in critical condition and died on 08 Apr 2013. Exposed to healthy pigeons and neighbourhood poultry. The fourth case in 2013, 25 years old female, from Sohaq province. She developed symptoms on 25 April, hospitalized on 29 April and died on 05 May 2013. She was exposed to sick and dead backyard poultry.

Viet Nam.The first case, 4 years old male, hamlet 1, Tan Hoi Trung commune, Cao Lanh district of Dong Thap province, onset 23 Mar 2013, admitted to Cao Lanh District hospital on 30 Mar and transferred to Provincial hospital of Dong Thap on 01 Apr, and died on 04 Apr 2013. The respiratory samples of this patient were confirmed by NIC of PIHCM on 05 Apr 2013. He had exposure to sick chicken on 25 Mar 2013.The second case, 20 year-old female, in Tan Hung district, Long An Province, onset on 11 April 2013, admitted to hospital on 14 April 2013 and transferred to Cho Ray Hospital on 15 April 2013. The respiratory samples of this patient were confirmed as A (H5N1) on 18 Apr 2013. She had exposure to sick duck. Response activities included enhanced surveillance and risk communication. The patient has fully recovered and no further cases were detected from the case’s community.

Latest information on avian influenza A (H5N1) outbreaks in animals

Source:

  • OIE WAHID Weekly Disease Information Reports
    http://web.oie.int/wahis/public.php?page=home
  • FAO ECTAD HPAI SITUATION UPDATE (EMPRES/GLEWS); official report ONLY
  • Update on Avian Influenza in Animals (Type H5)
    http://www.oie.int/animal-health-in-the-world/update-on-avian-influenza/2012/
  • Official Report from the Ministry of Agriculture/Livestock

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